eLife 27 ene 2026 Microglia replacement by ER-Hoxb8 conditionally immortalized macrophages provides insight into Aicardi–Goutières syndrome neuropathology
eLife 27 ene 2026 Directed differentiation of functional corticospinal-like neurons from endogenous SOX6+/NG2+ cortical progenitors
eLife 27 ene 2026 Synaptic mechanisms modulate the spatiotemporal dynamics of striatal direct pathway neurons and motor output
eLife 26 ene 2026 Axonal distribution of mitochondria maintains neuronal autophagy during aging via eIF2β
eLife 26 ene 2026 Phenylhydrazone-based endoplasmic reticulum proteostasis regulator compounds with enhanced biological activity
eLife 23 ene 2026 Doubling dolutegravir dosage reduces the viral reservoir in ART-treated people with HIV
eLife 23 ene 2026 HIV-specific CD8+ T-cell proliferative response 24 weeks after early antiretroviral therapy initiation is associated with the subsequent reduction in the viral reservoir
eLife 23 ene 2026 The IBEX knowledge-base a community resource enabling adoption and development of immunofluorescence imaging methods
eLife 23 ene 2026 Computational modelling identifies key determinants of subregion-specific dopamine dynamics in the striatum
eLife 22 ene 2026 A titin missense variant drives atrial electrical remodeling and is associated with atrial fibrillation
eLife 21 ene 2026 Shifting the PPARγ conformational ensemble toward a transcriptionally repressive state improves covalent inhibitor efficacy
eLife 21 ene 2026 <i>cxcl18b</i>-defined transitional state-specific nitric oxide drives injury-induced Müller glia cell-cycle re-entry in the zebrafish retina
eLife 21 ene 2026 Ω-Loop mutations control dynamics of the active site by modulating the hydrogen-bonding network in PDC-3 β-lactamase