Astrocytes functionally integrate multiple synapses via specialized leaflet domains
#Lucas Benoit#Ines Hristovska#Nicolas Liaudet#Arnold Fertin#Milica Jevtic
Life Science News
Latest updates from the biotech and pharma world
Mitochondrial activity tunes nociceptor resilience to excitotoxicity
#Lin Yuan#David Julius#Publication date#November#Cell
A conserved mechanism for the retrieval of polyubiquitinated proteins from cilia
#Alan Brown#Publication date#November#Cell#Volume
A receptor antagonist counterbalances multiple systemin phytocytokines in tomato
#Nga Pham#Andreas Schaller#Judith Fliegmann#Matthias Erb#Thomas Boller
Stereo-seq V2: Spatial mapping of total RNA on FFPE sections with high resolution
#Xinya Zhang#Xin Huang#Mei Yang#Jing Guo#Tingting Cao
Culture-independent meta-pangenomics enabled by long-read metagenomics reveals associations with pediatric undernutrition
#Nicholas Allsing#Kenneth Maleta#Nolan Hartwick#Allen Mamerto#Caitriona Brennan
Hepatocyte metabolic adaptations during pregnancy and lactation
#Liu Yang#Yu-Heng Zhou#Tong-Yun Mao#Qi-Qi Zheng#Hou-Zao Chen
Vaccine induction of heterologous HIV-1-neutralizing antibody B cell lineages in humans
#Gilad Ofek#Nathaniel Erdmann#Kshitij Wagh#Bette Korber#Katayoun Mansouri
Ancient host-associated microbes obtained from mammoth remains
#Benjamin Guinet#Nikolay Oskolkov#Kelsey Moreland#Marianne Dehasque#Anders Angerbjörn
Extensive cross-species transmission of pathogens and antibiotic resistance genes in mammals neglected by public health surveillance
#Yuqi Shi#Ayidana Haerheng#Philippe Lemey#Jia Tang#Publication date
Evolution of Mycobacterium tuberculosis transcription regulation is associated with increased transmission and drug resistance
#Qingyun Liu#Roger Calderon#Leonid Lecca#Maxine Caws#Phan Vuong
AI mirrors experimental science to uncover a mechanism of gene transfer crucial to bacterial evolution
#Juraj Gottweis#Alexander Daryin#Anil Palepu#Artiom Myaskovsky#Annalisa Pawlosky
Chimeric infective particles expand species boundaries in phage-inducible chromosomal island mobilization
#Jinlong Wang#Laura Miguel-Romero#Publication date#November#Cell
SNARE Proteins Are Required for Macroautophagy
#Usha Nair#Anjali Jotwani#Jiefei Geng#Noor Gammoh#Diana Richerson
Mucosal viral infection elicits long-lived IgA responses via type 1 follicular helper T cells
#Kei Haniuda#Yuko Makita#Sandhya Appiah#Thamotharampillai Dileepan#Publication date
Macrophage-targeted immunocytokine leverages myeloid, T, and NK cell synergy for cancer immunotherapy
#Pascale Zwicky#Ken Xie#Fadi Sheban#Adam Yalin#Florian Uhlitz
Elucidating pathway-selective biased CCKBR agonism for Alzheimer’s disease treatment
#Yue Shao#Hui Lin#Jie Cheng#Pan Shang#Fan Yang
BRAIN-MAGNET: A functional genomics atlas for interpretation of non-coding variants
#Ruizhi Deng#Elena Perenthaler#Anita Nikoncuk#Soheil Yousefi#Kristina Lanko
Single-cell susceptibility to viral infection is driven by variable cell states
#Sam Reffsin#Jesse Miller#Kasirajan Ayyanathan#Yael Heyman#Naveen Jain
Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia
#Emily Gruber#Rheana Franich#Jessica Armstrong#Léa Flippe#Kevin Wijanarko