Does the liver talk to the brain? If so, how and why?
#liver talk#interoceptive signals#liver#brain#including nutrients
Life Science News
Latest updates from the biotech and pharma world
In defense of pleasure: We need to rethink food reward and obesity
#food reward#overeating driven#food#obesity epidemic#rethink food
Interoception as a central mechanism in Whole Person Health
#Person Health#Langevin Interoception#central mechanism#key mechanism#Person
Evolving life-history traits promote biodiversity via eco-evolutionary feedback mechanisms
#Claudia Bank#Catalina Chaparro-Pedraza#life history#Evolving life-history#history
The body sends a signal: Perspectives on interoception
#PLOS Biology#Biology staff#staff editors#field unites#editors Research
Cell2Spatial is a computational framework that maps single cells to spatial transcriptomic spots to reconstruct tissue architecture
#Jingchao Liu#Zhenyu Liu#Yiyao Liu#Guige Wang#Meng Cao
The blood–brain barrier regulates brain tumor growth through the SLC36 amino acid transporter Pathetic in Drosophila
#Paul Orih#Hina Kosakamoto#Fumiaki Obata#Cyrille Alexandre#Qian Dong
Hydroxyurea induces an oxidative stress response that triggers ER expansion and cytoplasmic protein aggregation
#Manuel Bernal#Elena Hidalgo#Henar Valdivieso#Silvia Salas-Pino#Ana Sánchez-Molina
Chromosome duplication causes premature aging via defects in ribosome quality control
#James Hose#Hollis Howe#Norah Paulsen#Michael Place#lifelong problems
Transient frontopolar cortex stimulation induces prolonged disruption to counterfactual processing
#Carlos Pedreira#Matthew Ainsworth#frontopolar cortex#Buckley Frontopolar#Transient frontopolar
Bacterial immune systems as causes and consequences of microbiome structure
#Rafael Custodio#Westra Attacks#immune systems#Bacterial immune#genetic elements
Development of bitopic nanobody-ligand conjugates targeting G protein-coupled receptors and exhibiting logic-gated signaling
#Swarnali Roy#Shivani Sachdev#protein-coupled receptors#largest family#plasma membrane-embedded
Sleep deprivation and sleep intensity exert distinct effects on cerebral vasomotion and brain pulsations driven by the respiratory and cardiac cycles
#Brice Ozenne#Pia Weikop#Simone Pleinert#Vesa Kiviniemi#Maiken Nedergaard
Diverse biophysical and molecular mechanisms drive phytoplankton sinking in response to starvation
#Margaret Bisher#Reshum Aurora#Lam#gravitational sinking#sinking
Eye blinks synchronize with musical beats during music listening
#Xiangbin Teng#human behavior#incompletely understood#body movements#rhythmic patterns
STUPPIT is a proximity labeling tool for labeling intermediary proteins that bridge two non-interacting proteins
#Lijuan Gao#Lin Xie#Wenxiu Ning#Ning Decoding#intermediary proteins
Editorial Note: Global Regulator SATB1 Recruits β-Catenin and Regulates TH2 Differentiation in Wnt-Dependent Manner
#Global Regulator#Biology Editors#Editorial Note#PLOS Biology#Recruits β-Catenin
RNG2 tethers the conoid to the apical polar ring in Toxoplasma gondii to enable parasite motility and invasion
#Toxoplasma gondii#Bingjian Ren#Alessandro Bonavoglia#Rémy Visentin#Bohumil Maco
The cell cycle regulator PLK1 promotes murine melanoma progression by regulating the transcription factor BACH1
#Yanquan Zhang#Xinyi Wang#Qiongsi Zhang#Chi Wang#Yifan Kong
Amyloid precursor protein modulates cerebellar Purkinje cell activity and motor function through regulation of Nav1.6 currents
#Huanyao Tang#Jiao Yang#Xin Tang#Chenhao Tian#Xiang Cao