Genome sequences of extant and extinct gibbons reveal their phylogeny, demographic history, and conservation status
#Sheng Wang#Zehui Chen#Ayun Luo#Mukesh Thakur#Govindhaswamy Umapathy
Life Science News
Latest updates from the biotech and pharma world
Time-resolved reprogramming of single somatic cells into totipotent states during plant regeneration
#Yue Gao#Chao Qin#Xin Tian#Rahul Shaw#Keke Xia
Phase separation to buffer growth-mediated dilution in synthetic circuits
#Wangfei Yang#Amanda Godar#Sadikshya Rijal#Abdelrahaman Youssef#Wenwei Zheng
Pathway-selective 5-HT1AR agonist as a rapid antidepressant strategy
#Yujie Shao#Meng Gao#Yaqi Liang#Tian Xue#Yiming Shi
Longitudinal ultrasensitive ctDNA monitoring for high-resolution lung cancer risk prediction
#Publication date#prediction Publication#Longitudinal ultrasensitive#November#Takahiro Karasaki
Bridging single cells to organs: Mesoscale modules as fundamental units of tissue function
#Yun Chen#Pedro Lowenstein#Publication date#Mesoscale modules#function Publication
Molecular grammars of predicted intrinsically disordered regions that span the human proteome
#Vicky Liu#Avnika Pant#Cigall Kadoch#Min Kyung#Kyung Shinn
Remembering David Baltimore (1938–2025)
#David Baltimore#Publication date#Remembering David#November#Cell
Creeping fat-derived mechanosensitive fibroblasts drive intestinal fibrosis in Crohn’s disease strictures
#Benjamin Pham#Michelle Griffin#Alexia Kim#Michael Januszyk#Yue Xing
Molecular impact of antisense oligonucleotide therapy in C9orf72-associated ALS
#ALS Publication#Publication date#Molecular impact#November#Cell
Anti-BCMA CAR-T therapy in patients with progressive multiple sclerosis
#Chuan Qin#Jun Xiao#Wei Wang#Gerd Meyer#Ming-Hao Dong
Genomic atlas of 8,105 accessions reveals stepwise domestication, global dissemination, and improvement trajectories in soybean
#Zhou Zhu#Chao Fang#Xiaoyue Yang#Shuhui Song#Yalin Wang
Shank3 oligomerization governs material properties of the postsynaptic density condensate and synaptic plasticity
#Bowen Jia#Zeyu Shen#Shihan Zhu#Jingguo Huang#Zhitao Liao
Astrocytes functionally integrate multiple synapses via specialized leaflet domains
#Lucas Benoit#Ines Hristovska#Nicolas Liaudet#Arnold Fertin#Milica Jevtic
Mitochondrial activity tunes nociceptor resilience to excitotoxicity
#Lin Yuan#David Julius#Publication date#November#Cell
A conserved mechanism for the retrieval of polyubiquitinated proteins from cilia
#Alan Brown#Publication date#November#Cell#Volume
A receptor antagonist counterbalances multiple systemin phytocytokines in tomato
#Nga Pham#Andreas Schaller#Judith Fliegmann#Matthias Erb#Thomas Boller
Stereo-seq V2: Spatial mapping of total RNA on FFPE sections with high resolution
#Xinya Zhang#Xin Huang#Mei Yang#Jing Guo#Tingting Cao
Culture-independent meta-pangenomics enabled by long-read metagenomics reveals associations with pediatric undernutrition
#Nicholas Allsing#Kenneth Maleta#Nolan Hartwick#Allen Mamerto#Caitriona Brennan
Hepatocyte metabolic adaptations during pregnancy and lactation
#Liu Yang#Yu-Heng Zhou#Tong-Yun Mao#Qi-Qi Zheng#Hou-Zao Chen