Bacterial immune systems as causes and consequences of microbiome structure
#Rafael Custodio#Westra Attacks#immune systems#Bacterial immune#genetic elements
Life Science News
Latest updates from the biotech and pharma world
Development of bitopic nanobody-ligand conjugates targeting G protein-coupled receptors and exhibiting logic-gated signaling
#Swarnali Roy#Shivani Sachdev#protein-coupled receptors#largest family#plasma membrane-embedded
Sleep deprivation and sleep intensity exert distinct effects on cerebral vasomotion and brain pulsations driven by the respiratory and cardiac cycles
#Brice Ozenne#Pia Weikop#Simone Pleinert#Vesa Kiviniemi#Maiken Nedergaard
Diverse biophysical and molecular mechanisms drive phytoplankton sinking in response to starvation
#Margaret Bisher#Reshum Aurora#Lam#gravitational sinking#sinking
Eye blinks synchronize with musical beats during music listening
#Xiangbin Teng#human behavior#incompletely understood#body movements#rhythmic patterns
STUPPIT is a proximity labeling tool for labeling intermediary proteins that bridge two non-interacting proteins
#Lijuan Gao#Lin Xie#Wenxiu Ning#Ning Decoding#intermediary proteins
Editorial Note: Global Regulator SATB1 Recruits β-Catenin and Regulates TH2 Differentiation in Wnt-Dependent Manner
#Global Regulator#Biology Editors#Editorial Note#PLOS Biology#Recruits β-Catenin
RNG2 tethers the conoid to the apical polar ring in Toxoplasma gondii to enable parasite motility and invasion
#Toxoplasma gondii#Bingjian Ren#Alessandro Bonavoglia#Rémy Visentin#Bohumil Maco
The cell cycle regulator PLK1 promotes murine melanoma progression by regulating the transcription factor BACH1
#Yanquan Zhang#Xinyi Wang#Qiongsi Zhang#Chi Wang#Yifan Kong
Amyloid precursor protein modulates cerebellar Purkinje cell activity and motor function through regulation of Nav1.6 currents
#Huanyao Tang#Jiao Yang#Xin Tang#Chenhao Tian#Xiang Cao
The efficacy of longevity interventions in Caenorhabditis elegans is determined by the early life activity of RNA splicing factors
#Caroline Heintz#Mary Piper#Meeta Mistry#Arpit Sharma#Hannah Smith
Efficient and reliable spike sorting from neural recordings with UMAP-based unsupervised nonlinear dimensionality reduction
#Lucas Bayones#Sergio Parra#Viktor Monroy#Sebastián Pujalte#Héctor Díaz
Benchmarking with synthetic communities provides a baseline for virus-host inferences from Hi-C proximity linking
#Nurani Shatadru#Rokaiya Nurani#Sullivan Microbiomes#Microbiomes influence#diverse ecosystems
Cardiometabolic health and physical robustness map onto distinct patterns of brain structure and neurotransmitter systems
#Mostafa Mahdipour#Agoston Mihalik#Mahnaz Olfati#Felix Hoffstaedter#Masoud Tahmasian
Nanobody-drug conjugates for targeting specific GPCR pairs
#Xianglin Huang#specific GPCR#Roth Bitopic#GPCR pairs#PLOS Biology