抑制PRMT活性增强同源重组功能正常的卵巢癌和乳腺癌细胞对PARP抑制剂的敏感性
Repression of PRMT activities sensitize human homologous recombination-proficient ovarian and breast cancer cells to PARP inhibitor treatment
生物技术与制药领域的最新动态
Repression of PRMT activities sensitize human homologous recombination-proficient ovarian and breast cancer cells to PARP inhibitor treatment
The chromatin remodeller CHD4 regulates transcription factor binding to both prevent activation of silent enhancers and maintain active regulatory elements
Automatic learning mechanisms for flexible human locomotion
The Drosophila EGF domain protein uninflatable sets the switch between wrapping glia growth and axon wrapping instructed by Notch
Mixture discrimination training induces durable and generalizable olfactory learning independent of odorant structure and concentration
Single-nucleus transcriptional and chromatin accessibility analyses of maturing mouse Achilles tendon uncover the molecular landscape of tendon stem/progenitor cells
Information, certainty, and learning
Polymorphisms in intron 1 of HLA-DRA differentially associate with type 1 diabetes and celiac disease and implicate involvement of complement system genes C4A and C4B
MRI sets its sights on collagen
The representation of facial emotion expands from sensory to prefrontal cortex with development
A forebrain hub for cautious actions via the midbrain
Causal evidence for a domain-specific role of left superior frontal sulcus in human perceptual decision-making
Accelerated evolution in networked metapopulations of Pseudomonas aeruginosa
Human brain dynamics and spatiotemporal trajectories during threat processing
Retraction: PAK3 downregulation induces cognitive impairment following cranial irradiation
Single-cell transcriptomics identifies altered neutrophil dynamics and accentuated T-cell cytotoxicity in tobacco-flavored e-cigarette-exposed mouse lungs
Correction: Down-regulated GAS6 impairs synovial macrophage efferocytosis and promotes obesity-associated osteoarthritis
Feeding rates in sessile versus motile ciliates are hydrodynamically equivalent
Branched actin polymerization drives invasive protrusion formation to promote myoblast fusion during mouse skeletal muscle regeneration
Mitochondrial protein carboxyl-terminal alanine-threonine tailing promotes human glioblastoma growth by regulating mitochondrial function