生命科学资讯

Zebrafish use spectral information to suppress the visual background

Generation of antigen-specific paired-chain antibodies using large language models

Gut-to-brain signaling restricts dietary protein intake during recovery from catabolic states

Disparate leukemia mutations converge on nuclear phase-separated condensates

Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer

Mapping chromatin structure at base-pair resolution unveils a unified model of cis-regulatory element interactions

StealTHY: An immunogen-free CRISPR platform to expose concealed metastasis regulators in immunocompetent models

Genome sequences of extant and extinct gibbons reveal their phylogeny, demographic history, and conservation status

Time-resolved reprogramming of single somatic cells into totipotent states during plant regeneration

Phase separation to buffer growth-mediated dilution in synthetic circuits

Pathway-selective 5-HT1AR agonist as a rapid antidepressant strategy

Longitudinal ultrasensitive ctDNA monitoring for high-resolution lung cancer risk prediction

Bridging single cells to organs: Mesoscale modules as fundamental units of tissue function

Molecular grammars of predicted intrinsically disordered regions that span the human proteome

Remembering David Baltimore (1938–2025)

Creeping fat-derived mechanosensitive fibroblasts drive intestinal fibrosis in Crohn’s disease strictures

Molecular impact of antisense oligonucleotide therapy in C9orf72-associated ALS

Anti-BCMA CAR-T therapy in patients with progressive multiple sclerosis

Genomic atlas of 8,105 accessions reveals stepwise domestication, global dissemination, and improvement trajectories in soybean

Shank3 oligomerization governs material properties of the postsynaptic density condensate and synaptic plasticity