生命科学资讯

The cellular logic of limb regeneration

Western lifestyle linked to maladaptive trained immunity

Shifting the PPARγ conformational ensemble toward a transcriptionally repressive state improves covalent inhibitor efficacy

Anti-resonance in developmental signaling regulates cell fate decisions

cxcl18b-defined transitional state-specific nitric oxide drives injury-induced Müller glia cell-cycle re-entry in the zebrafish retina

Ω-Loop mutations control dynamics of the active site by modulating the hydrogen-bonding network in PDC-3 β-lactamase

Identification of a sub-population of synovial mesenchymal stem cells with enhanced treatment efficacy in a rat model of osteoarthritis

ATAD2 mediates chromatin-bound histone chaperone turnover

Modeling and simulation of neocortical micro- and mesocircuitry (Part I, anatomy)

Modeling and simulation of neocortical micro- and mesocircuitry (Part II, Physiology and experimentation)

Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatment

GMCL1 controls 53BP1 stability and modulates taxane sensitivity

A high-resolution analysis of arrestin2 interactions responsible for CCR5 endocytosis

Predicting human decision-making across task conditions via individuality transfer

Linking neuron-glia interactions and longevity

Glial betaPix is essential for blood vessel development in the zebrafish brain

Stratification of viral shedding patterns in saliva of COVID-19 patients

Targeted computational design of an interleukin-7 superkine with enhanced folding efficiency and immunotherapeutic efficacy