抑制寡聚BAX的抗凋亡二聚体作用
Inhibition of oligomeric BAX by an anti-apoptotic dimer
#Haleh Alimohamadi#Publication date#oligomeric BAX#dimer Publication#November
生命科学资讯
生物技术与制药领域的最新动态
人类血管类器官发育过程中的命运与状态转变
Fate and state transitions during human blood vessel organoid development
#Makiko Seimiya#Gustav Jonsson#Wuji Cao#Ryo Okuda#Ryoko Okamoto
已灭绝猛犸象的古代RNA表达谱
Ancient RNA expression profiles from the extinct woolly mammoth
#Bastian Fromm#Nikolay Oskolkov#Zoé Pochon#Marianne Dehasque#Morteza Aslanzadeh
药物扰动下营养竞争预测肠道微生物组重构
Nutrient competition predicts gut microbiome restructuring under drug perturbations
#Handuo Shi#Sylvie Estrela#Juan Sanchez#Qinglin Zeng#Publication date
制药业面临向最高法院提起IRA诉讼的最后期限，首批议定价格即将出台
Pharma faces deadline to bring IRA fight to Supreme Court as first set of negotiated prices looms
辉瑞mRNA流感疫苗三期数据显示其效力比标准疫苗高出34.5%
Pfizer's mRNA flu vaccine shows 34.5% greater efficacy than standard shot in phase 3
#mRNA flu#Pfizer mRNA#flu vaccine#greater efficacy#greater effectiveness
疾控中心更新网站称疫苗可能引发自闭症，但无新证据支持
CDC updates website to say vaccines may cause autism without new evidence
#CDC updates#updates website#webpage undercut#medical community#community consensus
库珀公司面临激进投资者压力，考虑分拆方案各异
The Cooper Companies under activist pressure to split—in different ways
#Cooper Companies#past month#activist pressure#Activist investors#outlined dueling
Moderna继续重组，再砍三条研发管线
Moderna's reshaping rolls on with 3 more pipeline purges
#Moderna reshaping#vaccine Spikevax#pipeline purges#infectious diseases#mRNA programs
与RFK Jr.的“健康思想交流”如何推动了FDA的基因疗法进程
How a 'healthy exchange of ideas' with RFK Jr. kick-started FDA's gene therapy push
#Tim Hunt#Human Services#early March#kick-started FDA#FDA gene
GE医疗将以23亿美元收购影像软件供应商Intelerad
GE HealthCare to acquire imaging software provider Intelerad for $2.3B
#cardiology practices#clinical trials#provider Intelerad#imaging business#software provider
《Fierce Biotech 2025年裁员追踪：Applied Tx裁员46%；Ensoma亦进行人员削减》
Fierce Biotech Layoff Tracker 2025: Applied Tx lays off 46% of staff; Ensoma makes cuts
#Fierce Biotech#Layoff Tracker#Ensoma makes#makes cuts#editorial team
生物科技CEO们致信马卡里，呼吁FDA保持稳定，称波动性威胁美国创新
In letter to Makary, biotech CEOs push for FDA stability and say volatility threatens US innovation
#Marty Makary#Director Marty#FDA Director#FDA stability#biotech CEOs
Contineum与强生合作的多发性硬化症药物在二期试验中未能改善视力
Contineum's J&J-partnered MS drug fails to improve vision in phase 2
#Contineum Therapeutics’#receptor antagonist#multiple sclerosis#drug fails#common form
FDA宣布增聘逾千名员工并启动审评流程新沟通计划
FDA says it's hiring more than 1,000 new staffers, launches new comms program for review process
#review process#pilot communication#comms program#communication program#FDA
葛兰素史克旗下Tesaro与AnaptysBio因Jemperli协议对簿公堂
GSK's Tesaro, AnaptysBio lock horns in court over Jemperli agreement
#GSK Tesaro#Jemperli agreement#GSK subsidiary#subsidiary Tesaro#life span
Nurix启动主要BTK降解剂关键试验之际裁员
Nurix trims workforce as pivotal trial for lead BTK degrader kicks off
#Nurix Therapeutics#Nurix trims#BTK degrader#cancer asset#lead BTK
罗氏签署超2亿美元许可协议，引进Freenome癌症筛查血液检测技术
Roche inks $200M-plus licensing pact for Freenome's cancer screening blood tests
#Roche inks#licensing pact#million equity#Freenome cancer#blood tests
吉列德突然与总法律顾问分道扬镳
Chutes & Ladders—Gilead abruptly parts ways with general counsel
#Deborah Telman#filing Nov.#Gilead abruptly#general counsel#affairs Deborah
CDC指示研究人员年底前终止所有猴子研究：《科学》
CDC instructs researchers to end all monkey studies by year-end: Science
#Science reported#CDC instructs#instructs researchers#instructing scientists#research involving