生命科学资讯

Multiscale proteomic modeling reveals protein networks driving Alzheimer’s disease pathogenesis

Human monoclonal antibodies targeting A35 protect from death caused by mpox

IL-25-induced memory type 2 innate lymphoid cells enforce mucosal immunity

Transient gene melting governs the timing of oligodendrocyte maturation

Structural basis of poxvirus fusion regulation and anti-A16/G9 antibody-mediated neutralization and protection

Structurally conserved human anti-A35 antibodies protect mice and macaques from mpox virus infection

Functional RNA splitting drove the evolutionary emergence of type V CRISPR-Cas systems from transposons

RNA Pol II inhibition activates cell death independently from the loss of transcription

Glycan shielding enables TCR-sufficient allogeneic CAR-T therapy

Tumors hijack macrophages for iron supply to promote bone metastasis and anemia

A unified cell atlas of vascular plants reveals cell-type foundational genes and accelerates gene discovery

Charting the landscape of cytoskeletal diversity in microbial eukaryotes

Coalescing single-cell genomes and transcriptomes to decode breast cancer progression

Zebrafish use spectral information to suppress the visual background

Generation of antigen-specific paired-chain antibodies using large language models

Gut-to-brain signaling restricts dietary protein intake during recovery from catabolic states

Disparate leukemia mutations converge on nuclear phase-separated condensates

Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer

Mapping chromatin structure at base-pair resolution unveils a unified model of cis-regulatory element interactions

StealTHY: An immunogen-free CRISPR platform to expose concealed metastasis regulators in immunocompetent models