生命科学资讯

Genome sequences of extant and extinct gibbons reveal their phylogeny, demographic history, and conservation status

Time-resolved reprogramming of single somatic cells into totipotent states during plant regeneration

Phase separation to buffer growth-mediated dilution in synthetic circuits

Pathway-selective 5-HT1AR agonist as a rapid antidepressant strategy

Longitudinal ultrasensitive ctDNA monitoring for high-resolution lung cancer risk prediction

Bridging single cells to organs: Mesoscale modules as fundamental units of tissue function

Molecular grammars of predicted intrinsically disordered regions that span the human proteome

Remembering David Baltimore (1938–2025)

Creeping fat-derived mechanosensitive fibroblasts drive intestinal fibrosis in Crohn’s disease strictures

Molecular impact of antisense oligonucleotide therapy in C9orf72-associated ALS

Anti-BCMA CAR-T therapy in patients with progressive multiple sclerosis

Genomic atlas of 8,105 accessions reveals stepwise domestication, global dissemination, and improvement trajectories in soybean

Shank3 oligomerization governs material properties of the postsynaptic density condensate and synaptic plasticity

Astrocytes functionally integrate multiple synapses via specialized leaflet domains

Mitochondrial activity tunes nociceptor resilience to excitotoxicity

A conserved mechanism for the retrieval of polyubiquitinated proteins from cilia

A receptor antagonist counterbalances multiple systemin phytocytokines in tomato

Stereo-seq V2: Spatial mapping of total RNA on FFPE sections with high resolution

Culture-independent meta-pangenomics enabled by long-read metagenomics reveals associations with pediatric undernutrition

Hepatocyte metabolic adaptations during pregnancy and lactation