by Susmit Mhatre, Darcie L. Moore The field of human adult neurogenesis has been controversial despite mounting evidence. The authors propose moving beyond debating the existence of adult neurogenesis and towards discovering strategies to harness endogenous stem cell potential for resilience against cognitive aging. The field of human adult neurogenesis has been controversial despite mounting evidence. This Perspective proposes moving beyond debating the existence of adult neurogenesis, and towards discovering strategies to harness endogenous stem cell potential for resilience against cognitive aging.