PLoS Biology November 25, 2025

The body sends a signal: Perspectives on interoception

by Lucas K. Smith, on behalf of the PLOS Biology staff editors Research into brain–body communication is being reinvigorated as the field unites under the umbrella of “interoception.” In this issue of PLOS Biology, four Perspectives show the breadth of this emerging field, highlighting how interoceptive pathways might be used to promote health. Research into brain–body communication is being reinvigorated as the field unites under the umbrella of ‘interoception’. This Editorial highlights fou