生命科学资讯

Bacterial immune systems as causes and consequences of microbiome structure

Development of bitopic nanobody-ligand conjugates targeting G protein-coupled receptors and exhibiting logic-gated signaling

Sleep deprivation and sleep intensity exert distinct effects on cerebral vasomotion and brain pulsations driven by the respiratory and cardiac cycles

Diverse biophysical and molecular mechanisms drive phytoplankton sinking in response to starvation

Eye blinks synchronize with musical beats during music listening

STUPPIT is a proximity labeling tool for labeling intermediary proteins that bridge two non-interacting proteins

Editorial Note: Global Regulator SATB1 Recruits β-Catenin and Regulates TH2 Differentiation in Wnt-Dependent Manner

RNG2 tethers the conoid to the apical polar ring in Toxoplasma gondii to enable parasite motility and invasion

The cell cycle regulator PLK1 promotes murine melanoma progression by regulating the transcription factor BACH1

Amyloid precursor protein modulates cerebellar Purkinje cell activity and motor function through regulation of Nav1.6 currents

The efficacy of longevity interventions in Caenorhabditis elegans is determined by the early life activity of RNA splicing factors

Efficient and reliable spike sorting from neural recordings with UMAP-based unsupervised nonlinear dimensionality reduction

Benchmarking with synthetic communities provides a baseline for virus-host inferences from Hi-C proximity linking

Cardiometabolic health and physical robustness map onto distinct patterns of brain structure and neurotransmitter systems

Nanobody-drug conjugates for targeting specific GPCR pairs

Collaborative rule learning promotes interbrain information alignment

Episodic memory involves transient and sparse connectivity aligned to both internal and external events

The novel GlcNAc 6-phosphate dehydratase NagS governs a metabolic checkpoint that controls nutrient signaling in Streptomyces

Context-dependent activation of V1 parvalbumin interneurons enhances visual discrimination

A novel targeting domain directs essential components of the cytosolic iron–sulfur cluster assembly pathway to the mitochondrion of Toxoplasma parasites