PLoS Biology 2025年11月25日

RNG2将弓形虫的锥体结构锚定于顶端极环,以驱动寄生虫的运动与侵袭能力

by Romuald Haase, Bingjian Ren, Albert Tell i Puig, Alessandro Bonavoglia, Jean-Baptiste Marq, Rémy Visentin, Nicolas Dos Santos Pacheco, Bohumil Maco, Ricardo Mondragón-Flores, Oscar Vadas, Dominique Soldati-Favre The conoid is a dynamic, tubulin-based structure conserved across the Apicomplexa that undergoes extrusion during egress, gliding motility, and invasion in Toxoplasma gondii. This organelle traverses the apical polar ring (APR) in response to calcium waves and plays a critical role i