生命科学资讯
生物技术与制药领域的最新动态
BICC1 interacts with PKD1 and PKD2 to drive cystogenesis in ADPKD
Correction: Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity
单细胞图谱揭示t(8;21)急性髓系白血病中与年龄相关的基因调控网络
Single-cell atlas of AML reveals age-related gene regulatory networks in t(8;21) AML
四位女性先驱者的科学贡献长期被忽视
Four women whose pioneering contributions to science have been largely overlooked
35项性状多基因指数与死亡率的异质性关联:一项基于登记链接人群的随访研究
Heterogeneous associations of polygenic indices of 35 traits with mortality: a register-linked population-based follow-up study
后向条件反射揭示边缘下皮层抑制性记忆的灵活性
Backward conditioning reveals flexibility in infralimbic cortex inhibitory memories
大鼠前额叶皮层2/3层反复兴奋性突触的短期促进源于可释放池的渐进性过度填充
Progressive overfilling of readily releasable pool underlies short-term facilitation at recurrent excitatory synapses in layer 2/3 of the rat prefrontal cortex
基于压缩感知的方法识别驱动习得性病原体回避的模块化神经回路
Compressed sensing-based approach identifies modular neural circuitry driving learned pathogen avoidance
掌控感能缓冲压力
Sense of control buffers against stress
<i>map3k1</i>基因是涡虫中祖细胞分化空间限制的必要条件
map3k1 is required for spatial restriction of progenitor differentiation in planarians
性肽靶向大脑中不同的高级处理神经元,以诱导雌性交配后反应。
Sex peptide targets distinct higher order processing neurons in the brain to induce the female post-mating response
非结构化α-微管蛋白C末端尾部的可及性受微管晶格构象调控
Accessibility of the unstructured α-tubulin C-terminal tail is controlled by microtubule lattice conformation
体内自发荧光寿命成像揭示果蝇蘑菇体空间代谢异质性及学习诱导变化
In vivo autofluorescence lifetime imaging of spatial metabolic heterogeneities and learning-induced changes in the Drosophila mushroom body
抗Aβ抗体的聚集依赖性表位序列与修饰指纹图谱
Aggregation-dependent epitope sequence and modification fingerprints of anti-Aβ antibodies
小鼠感觉运动皮层在伸抓过程中反映复杂的运动学细节
Mouse sensorimotor cortex reflects complex kinematic details during reaching and grasping
西酞普兰通过调节C5aR1<sup>+</sup> TAMs展现免疫依赖性抗肿瘤效应
Citalopram exhibits immune-dependent anti-tumor effects by modulating C5aR1+ TAMs
小鼠骨骼肌卫星细胞利用肌腱生成基因<i>Scleraxis</i>指导再生
Mouse skeletal muscle satellite cells co-opt the tenogenic gene Scleraxis to instruct regeneration
重新定义感觉运动皮层的边界
Redefining borders in the sensorimotor cortex
糖酵解依赖性硫代谢调控真菌形态可塑性与毒力
Glycolysis-dependent sulfur metabolism orchestrates morphological plasticity and virulence in fungi