PLoS Biology 2025年11月25日

睡眠不足与睡眠深度对呼吸和心脏周期驱动下的脑血管运动及脑搏动具有不同影响

by Sara Marie Ulv Larsen, Sebastian Camillo Holst, Anders Stevnhoved Olsen, Brice Ozenne, Dorte Bonde Zilstorff, Kristoffer Brendstrup-Brix, Pia Weikop, Simone Pleinert, Vesa Kiviniemi, Poul Jørgen Jennum, Maiken Nedergaard, Gitte Moos Knudsen The flow of cerebrospinal fluid (CSF) through the brain is driven by cerebral vasomotion, along with respiratory and cardiac forces. Growing evidence suggests that sleep facilitates this flow, yet the role of homeostatic sleep mechanisms remains largely u