by Wen G. Chen, Helene M. Langevin Interoception may be a key mechanism in “Whole Person Health.” More and better technologies, tools, and mechanistic research are needed to fully understand its role, as well as new interventions to promote healthy physiological self-regulation through interoceptive signals. Decoding the body’s internal signals could revolutionize Whole Person Health. This Perspective suggests a research framework linking brain, body and behavior to foster resilience, self-reg